产品货号:
Z25089
中文名称:
Renin/REN抗体
英文名称:
Anti-Renin/REN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Renin/REN Antibody |
指标别名 | Angiotensinogenase,REN,Renin |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,Direct ELISA |
基因名称 | REN |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human Renin/REN recombinant protein (Position:N80-D370). |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | This gene encodes renin,an aspartic protease that is secreted by the kidneys.Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure,and electrolyte balance.This enzyme catalyzes the first step in the activation pathway of angiotensinogen by cleaving angiotensinogen to form angiotensin I,which is then converted to angiotensin II by angiotensin I converting enzyme.This cascade can result in aldosterone release,narrowing of blood vessels,and increase in blood pressure as angiotension II is a vasoconstrictive peptide.Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described,but their full-length nature has not been determined.Mutations in this gene have been shown to cause hyperuricemic nephropathy familial juvenile 2,familial hyperproreninemia,and renal tubular dysgenesis. |
Uniprot ID | P00797 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
基因名全称 | renin |
蛋白名全称 | Renin |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Direct ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
Gene ID | 5972 |
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